Once my unemployment hits 6% I stop zoning and wait for my population to grow. It takes a little while to fill the new jobs and I get messages that there are not enough workers but the jobs do get filled before the factories are abandoned. I wait until my unemployment rate hits 12%, then I zone industrial. The key to accomplishing this has been maintaining a high unemployment rate. Almost everybody works in industry, in jobs that they are over qualified for. I have got it up to 75,000 population with almost no offices and the bare necessity of commercial zoning. I am working on my second city and I am attempting to build an industrial powerhouse.